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Abstract BackgroundEffective diabetes management requires precise glycemic control to prevent both hypoglycemia and hyperglycemia, yet existing machine learning (ML) and reinforcement learning (RL) approaches often fail to balance competing objectives. Traditional RL-based glucose regulation systems primarily focus on single-objective optimization, overlooking factors such as minimizing insulin overuse, reducing glycemic variability, and ensuring patient safety. Furthermore, these approaches typically rely on centralized data processing, which raises privacy concerns due to the sensitive nature of health care data. There is a critical need for a decentralized, privacy-preserving framework that can personalize blood glucose regulation while addressing the multiobjective nature of diabetes management. ObjectiveThis study aimed to develop and validate PRIMO-FRL (Privacy-Preserving Reinforcement Learning for Individualized Multi-Objective Glycemic Management Using Federated Reinforcement Learning), a novel framework that optimizes clinical objectives—maximizing time in range (TIR), reducing hypoglycemia and hyperglycemia, and minimizing glycemic risk—while preserving patient privacy. MethodsWe developed PRIMO-FRL, integrating multiobjective reward shaping to dynamically balance glucose stability, insulin efficiency, and risk reduction. The model was trained and tested using simulated data from 30 simulated patients (10 children, 10 adolescents, and 10 adults) generated with the Food and Drug Administration (FDA)–approved UVA/Padova simulator. A comparative analysis was conducted against state-of-the-art RL and ML models, evaluating performance using metrics such as TIR, hypoglycemia (<70 mg/dL), hyperglycemia (>180 mg/dL), and glycemic risk scores. ResultsThe PRIMO-FRL model achieved a robust overall TIR of 76.54%, with adults demonstrating the highest TIR at 81.48%, followed by children at 77.78% and adolescents at 70.37%. Importantly, the approach eliminated hypoglycemia, with 0.0% spent below 70 mg/dL across all cohorts, significantly outperforming existing methods. Mild hyperglycemia (180-250 mg/dL) was observed in adolescents (29.63%), children (22.22%), and adults (18.52%), with adults exhibiting the best control. Furthermore, the PRIMO-FRL approach consistently reduced glycemic risk scores, demonstrating improved safety and long-term stability in glucose regulation.. ConclusionsOur findings highlight the potential of PRIMO-FRL as a transformative, privacy-preserving approach to personalized glycemic management. By integrating federated RL, this framework eliminates hypoglycemia, improves TIR, and preserves data privacy by decentralizing model training. Unlike traditional centralized approaches that require sharing sensitive health data, PRIMO-FRL leverages federated learning to keep patient data local, significantly reducing privacy risks while enabling adaptive and personalized glucose control. This multiobjective optimization strategy offers a scalable, secure, and clinically viable solution for real-world diabetes care. The ability to train personalized models across diverse populations without exposing raw data makes PRIMO-FRL well-suited for deployment in privacy-sensitive health care environments. These results pave the way for future clinical adoption, demonstrating the potential of privacy-preserving artificial intelligence in optimizing glycemic regulation while maintaining security, adaptability, and personalization. 

With support from the National Science Foundation, The University of Washington Tacoma and North Dakota State University have developed scenario-based security curriculum and online showcase labs with interactive simulations and case studies across three progressive courses, revolutionizing cybersecurity education for Criminal Justice (CJ) professionals. By incorporating artificial intelligence into the curriculum, this project enhances CJ professionals’ capabilities. Our goal is to develop a skilled workforce of CJ professionals with cybersecurity and privacy knowledge, addressing the critical need for such cybersecurity expertise in CJ. Literature review, focus group survey results, course framework tailored for CJ professionals, example course modules, and implementation results are presented. 

The increasing adoption of smart home devices has raised significant concerns regarding privacy, security, and vulnerability to cyber threats. This study addresses these challenges by presenting a federated learning framework enhanced with blockchain technology to detect intrusions in smart home environments. The proposed approach combines knowledge distillation and transfer learning to support heterogeneous IoT devices with varying computational capacities, ensuring efficient local training without compromising privacy. Blockchain technology is integrated to provide decentralized, tamper-resistant access control through Role-Based Access Control (RBAC), allowing only authenticated devices to participate in the federated learning process. This combination ensures data confidentiality, system integrity, and trust among devices. This framework’s performance was evaluated using the N-BaIoT dataset, showcasing its ability to detect anomalies caused by botnets such as Mirai and BASHLITE across diverse IoT devices. Results demonstrate significant improvements in intrusion detection accuracy, particularly for resource-constrained devices, while maintaining privacy and adaptability in dynamic smart home environments. These findings highlight the potential of this blockchain-enhanced federated learning system to offer a scalable, robust, and privacy-preserving solution for securing smart homes against evolving threats. 

Background/Objective: Nutritionists play a crucial role in guiding individuals toward healthier lifestyles through personalized meal planning; however, this task involves navigating a complex web of factors, including health conditions, dietary restrictions, cultural preferences, and socioeconomic constraints. The Analytic Hierarchy Process (AHP) offers a valuable framework for structuring these multi-faceted decisions but inconsistencies can hinder its effectiveness in pairwise comparisons. Methods: This paper proposes a novel hybrid Particle Swarm Optimization–Simulated Annealing (PSO-SA) algorithm to refine inconsistent AHP weight matrices, ensuring a consistent and accurate representation of the nutritionist’s expertise and client preferences. Our approach merges PSO’s global search capabilities with SA’s local search precision, striking an optimal balance between exploration and exploitation. Results: We demonstrate the practical utility of our algorithm through real-world use cases involving personalized meal planning for individuals with specific dietary needs and preferences. Results showcase the algorithm’s efficiency in achieving consistency and surpassing standard PSO accuracy. Conclusion: By integrating the PSO-SA algorithm into a mobile app, we empower nutritionists with an advanced decision-making tool for creating tailored meal plans that promote healthier dietary choices and improved client outcomes. This research represents a significant advancement in multi-criteria decision-making for nutrition, offering a robust solution to the inconsistency challenge in AHP and paving the way for more effective and personalized dietary interventions. 

Methane (CH4) oxidation is an important reaction to reduce the greenhouse effect caused by incomplete combustion of CH4. Here, we explored the mechanism of CH4 oxidation catalyzed by CeO2 and Ni-doped CeO2, focusing on the redox properties of these catalyst surfaces, using density functional theory (DFT). We found that the barriers for CH4* activation and H2O* formation are correlated with the surface redox capacity, which is enhanced by Ni doping. Furthermore, the complete reaction mechanism is explored by DFT calculations and microkinetic simulations on bare and Ni-doped CeO2 surfaces. Our calculations suggest that the doping of Ni leads to a much higher overall reactivity, due to a balance between the CH4* activation and H2O* formation steps. These results provide insights into the CH4 oxidation mechanism and the intrinsic relationship between redox properties and the activity of CeO2 surfaces.